Hyperthermia can be divided into three fields: active (fever) and passive whole-body hyperthermia as well as local hyperthermia.
Whole-body hyperthermia:
During whole-body hyperthermia the whole body is heated up to temperatures of 39 to 40 ?C (moderate form) or 41.5 to 42.5 ?C (extreme form). Moderate long-term whole-body hyperthermia has the highest therapeutic effect in combination with chemotherapy and immunotherapy.
Local hyperthermia:
Local hyperthermia can be achieved by means of external intraluminal (=hollow organ such as e.g. the bladder) or interstitial (= within the organ tissue) methods. The external application of heat is used for surface and deep hyperthermia. Regional hyperthermia, e.g. with capacity-connected electrodes or radiative high frequency methods, can achieve partial hyperthermia.